Patrick trained at The Central School of Speech & Drama.

Theatre credits include: To Kill a Mockingbird (Gielgud Theatre, London) Macbeth (National Theatre), Woyzeck in Winter (Landmark Productions), Red (Prime Cut / Lyric Theatre Belfast), Quietly (Abbey Theatre/ Public Theater/ Irish Repertory/Soho Theatre/Traverse Theatre), Seven Acts of Mercy, Macbeth, (RSC), Antigone (Barbican/ Theatre de la Ville / BAM), Sixteen Possible Glimpses (Abbey Theatre), Titanic: Scenes From The British Wreck Commissioners Inquiry (MAC Belfast), The Crucible (Lyric Theatre, Belfast), Dr Faustus (Royal Exchange Theatre), The Crucible (Regents Park Theatre), Warhorse (National Theatre, West End), Whistle In The Dark (Royal Exchange Theatre), Cold Comfort, Ashes To Ashes, (Prime Cut Productions), Hamlet (Abbey Theatre), Insignificance (Sheffield Crucible Theatre), The Postman Always Rings Twice (West Yorkshire Playhouse), Scenes From The Big Picture, Closing Time, Peer Gynt, Romeo & Juliet, The Playboy Of The Western World (National Theatre) , Shoot The Crow (Royal Exchange Theatre), Medea, The House, As The Beast Sleeps, (Abbey Theatre), Trust, The Strip (Royal Court)).

Patrick O'Kane has been an Artistic Associate of Prime Cut Productions, and a NESTA Fellow and his book Actors’ Voices is published by Oberon

TV credits include: Doctor Who (BBC), Come Home (BBC), DCI Banks (ITV), The Secret (ITV), Vera (ITV), Jamaica Inn (BBC), Strike Back (Left Bank / Sky One), The Borgias (LB Productions), New Tricks (BBC), The Fall (BBC), Game of Thrones (HBO), Holby Blue (BBC), Wire in the Blood (Costal Productions), Five Days (BBC), IF... (BBC), Waking the Dead (BBC), Gunpowder, Treason and Plot (BBC), Any Time Now Nora Films), As The Beast Sleeps (BBC), In Deep (Valentine Productions), Liverpool One (ITV).

Film credits include: Female Human Animal, The Last Jedi, Boat, The Music Room, Prometheus, Perkins 14, Exorcist – The Beginnings, Octane, Stealing Rembrant, Though the Sky Falls, The Music Room (Short), The Boat (short), Limbo (short), Brilliance (short) and Charlottes Red (short).

Awards include: Red/Woyzeck In Winter – Best Actor – Irish Times Theatre Awards, Quietly – Best Actor – UK Theatre Awards/The Stage Awards/OFFIES As the Beast Sleeps – Best Supporting Actor, Irish Times Theatre Awards.